Two friends in a movie are not always harmonious off-screen relationships. Quite the contrary - it very often happens that two friends on the screen in life hate each other. Which of the celebrities had to play friendship on the set of a series or movie with their enemy? You did not expect this!

Joan Crawford & Bette Davis, What Ever Happened to Baby Jane?

The notorious feud between Crawford and Davis on the set of What Ever Happened to Baby Jane? was so intense that it became the subject of the first season of Ryan Murphy's anthology series, Feud. The rivalry between the Hollywood legends is said to have started when Crawford married Franchot Tone, who happened to be Davis' former love interest. "I have never forgiven her for that, and never will," Davis once remarked in an interview years later, describing her feelings towards Crawford.

Joan Crawford & Bette Davis – What Ever Happened to Baby Jane.jpg @What Ever Happened to Baby Jane? (1962) FULL MOVIE [Drama, Horror] Stars: Bette Davis, Joan Crawford/What Ever Happened to Baby Jan/YouTube.com

David Duchovny & Gillian Anderson, The X-Files

Behind the scenes of The X-Files, tensions ran high between the actors David Duchovny (Fox) and Gillian Anderson (Dana), despite their on-screen romance in nearly every episode. According to sources from 2008, the constant interaction between the two characters throughout the show's eight series led to frequent disagreements and conflicts. One of the actors expressed that the quarrels stemmed more from familiarity breeding contempt rather than any personal issues between them. They mentioned getting into fights about various matters and admitted to finding it difficult to be in the same room together.

David Duchovny & Gillian Anderson – The X-Files.jpg @David Duchovny And Gillian Anderson: Their Real Story | Rumour Juice/Rumour Juice/YouTube.com

Julia Roberts & Nick Nolte, I Love Trouble

Despite their on-screen chemistry in the film I Love Trouble, Julia Roberts and Nick Nolte reportedly had a strong dislike for each other. According to reports, their animosity was so intense that they had to film their scenes separately and use body doubles to create the illusion of on-screen chemistry in the 1994 film. Roberts, who portrayed Sabrina Peterson, later criticized Nolte (Peter Brackett) in an interview with The New York Times. She described him as "charming and nice" at times but also "completely disgusting." Roberts also revealed that they gave each other a hard time during the production of the film.

Julia Roberts & Nick Nolte – I Love Trouble.jpg @No se soportaban: Julia Roberts Vs. Nick Nolte/RjL/YouTube.com

Bruce Willis & Cybill Shepherd, Moonlighting

During its five-season run, the popular 1980s show Moonlighting thrived on the constant quarrels between the two main characters, private investigators Maddie Hayes and David Addison, as a way to conceal their undeniable physical attraction. However, according to Cybill Shepherd's later revelation to Entertainment Weekly, the off-screen relationship between herself and co-star Bruce Willis was more of a strained situation: “Maintaining relationships with everyone while working on a show can be challenging. I recall a point during the show where it had gotten to the extent that we genuinely disliked each other.”

Bruce Willis & Cybill Shepherd – Moonlighting.jpg @‘Very attracted to each other’ Cybill Shepherd on former Moonlighting co-star Bruce Willis/Healthy Lifestyle/YouTube.com

Nicollette Sheridan & Teri Hatcher, Desperate Housewives

In the popular TV series Desperate Housewives, there was a notable lack of camaraderie between Teri Hatcher and her co-stars Marcia Cross, Felicity Huffman, and Nicollette Sheridan. Teri, who portrayed the character Britt, was seen as the unofficial leader of the group. However, tensions arose among the actresses, and Teri's attempt to arrange a 2005 Vanity Fair cover shoot with the entire ensemble only seemed to exacerbate the situation. According to reports, Nicollette Sheridan referred to Hatcher as the "world's rudest lady," further fueling the animosity between them.

Nicollette Sheridan & Teri Hatcher – Desperate Housewives.jpg @Desperate Housewives Cast Still Love And Hate Each Other | Rumour Juice/Rumour Juice/YouTube.com

Dwayne “The Rock” Johnson & Vin Diesel, Fast and Furious

Despite the emphasis on family in the Fast and Furious franchise, the real-life relationship between Dwayne "The Rock" Johnson and Vin Diesel is far from harmonious. During Johnson's final week of filming The Fate of the Furious, he publicly criticized some of his male co-stars on Instagram. Additionally, reports surfaced claiming that Diesel influenced producers to remove a post-credit scene from Fate that would have set up a spin-off featuring Johnson and Jason Statham. The tension between the two actors suggests a lack of camaraderie off-screen.

Dwayne “The Rock” Johnson & Vin Diesel – Fast and Furious.jpg @The Entire Dwayne Johnson And Vin Diesel Feud Timeline Explained/Looper/Celebrity Star/YouTube.com

Ariana Grande & Victoria Justice, Victorious

Ariana Grande and Victoria Justice first met on the Nickelodeon show Victorious, in which they both had starring roles. Victoria once referred to Ariana as a "scene-stealer" during their time on the show. However, unlike the rest of the cast, Ariana did not include Victoria in her music video for Thank U, Next. Despite rumors of a feud between them over the years, Victoria seems unaffected by them. She expressed her disappointment in people's tendency to pit women against each other, stating, “It's disheartening to see how people enjoy creating conflicts between women.”

Ariana Grande & Victoria Justice – Victorious.jpg @Victoria Justice & Ariana Grande - L.A. Boyz [Victorious]/Erik Daniel C.A./YouTube.com

Taylor Momsen & Leighton Meester, Gossip Girl

In the series Gossip Girl, tensions didn't only arise between Serena and Blair. There were also reported conflicts between Taylor Momsen and Leighton Meester. Allegedly, the disagreement stemmed from the Gossip Girl production team favoring Leighton's music over Taylor's for the show. Leighton's songs, such as Good Girls Go Bad and Somebody To Love, were featured in two seasons of Gossip Girl, and her music video for Somebody To Love even premiered on the CW show. However, none of Momsen's music was used, causing friction between the two actresses.

Taylor Momsen & Leighton Meester – Gossip Girl.jpg @Gossip Girl Cast: Relationship They Have In Real Life | ⭐OSSA/OSSA/YouTube.com

Naya Rivera & Lea Michele, Glee

During the production of Fox's popular musical television show, the two female stars, Naya Rivera and Lea Michele, had an ongoing conflict. In 2014, a source revealed to reporters that they often had a cold relationship. There were feelings of envy from Naya towards Lea, who held the lead role in the show. There were instances of gossiping and eye-rolling between them. Another Glee actress, Amber Riley, who portrayed Mercedes Jones, also spoke out against some of Lea's controversies. Amber clarified that she was not accusing Lea of being prejudiced, but she expressed that she was not concerned about the controversy and focused on more significant global issues.

Naya Rivera & Lea Michele – Glee.jpg @glee cast hating lea michele for 5 minutes straight/payton/YouTube.com

Channing Tatum & Alex Pettyfer, Magic Mike

The on-screen mentorship between Channing Tatum and Alex Pettyfer in the film Magic Mike contrasts sharply with their real-life relationship. According to Pettyfer, there seems to be some animosity between the two actors. Pettyfer has openly admitted that Tatum does not like him, and he takes responsibility for it, acknowledging that he is at fault. The tension between them reportedly stems from Pettyfer renting an apartment from a friend of Tatum's and failing to pay several months' worth of rent before moving out. Tatum confronted Pettyfer about this matter through an email, understandably addressing the issue.

Channing Tatum & Alex Pettyfer – Magic Mike.jpg @Alex Pettyfer Claims Channing Tatum Doesn't Like Him -- Find Out Why/Entertainment Tonight/Celebrity Star/YouTube.com

Archie Panjabi & Julianna Margulies, The Good Wife

Speculations about a conflict between the principal female characters of The Good Wife had circulated for years, and in 2015, it appeared that those speculations were confirmed. Archie Panjabi, who played Kalinda Sharma, and Julianna Margulies, who portrayed Alicia Florrick, were on-screen best friends until a storyline involving betrayal in the second episode caused their characters to have limited interactions. Due to their alleged inability to work together, Panjabi and Margulies filmed their scenes separately, and their footage was later edited together to create the final sequence.

Archie Panjabi & Julianna Margulies – The Good Wife.jpg @Tv Best Friends Who Hated Each Other In Real Life /Toplaza/YouTube.com

Ian Somerhalder & Nina Dobrev, The Vampires Diaries

Following their three-year romance, the actors of The Vampire Diaries reportedly experienced a friendly breakup. However, things took a turn for the worse when Ian Somerhalder began dating one of Nina Dobrev's close friends. According to a source familiar with the situation, Nina decided to leave The Vampire Diaries because she found it too uncomfortable to continue working alongside Ian after their breakup. The source clarified that Nina wasn't seeking larger roles but simply couldn't bear the daily on-screen interaction with Ian.

@The Truth Behind Ian Somerhalder & Nina Dobrev's Heartbreaking Split | Rumour Juice/Access Hollywood/YouTube.com

Bella Thorne & Zendaya, The Shake-Up

Although Bella Thorne and Zendaya played best friends on-screen during their teenage years, Thorne has recently revealed the challenges they faced while working together on Disney Channel's Shake It Up in the early 2010s. Thorne opened up about feeling pitted against Zendaya and how it affected the friendship they were trying to build. In a new interview with US Weekly, Thorne admitted that she and Zendaya were not initially friends when they started filming the series in 2010, but an event eventually brought about a significant change in their relationship.

Bella Thorne & Zendaya – The Shake-Up.jpg @Zendaya and Bella Thorne Interview Each Other on the Set of K.C. Undercover/TigerBeat TV/YouTube.com

Betty White & Bea Arthur, Golden Girls

It is surprising to imagine anyone harboring animosity towards Betty White, but reportedly her Golden Girls co-star Bea Arthur found her cheerful personality irritating. Bea Arthur's feelings towards Betty White were no secret among the cast and crew of Golden Girls. As a result, Rue McClanahan, another cast member, expressed her disappointment and criticized Bea for using an offensive word against Betty.

Betty White & Bea Arthur – Golden Girls.jpg @Dark Secrets The Golden Girls Tried To Hide/EveryShow Review/YouTube.com

Martin Lawrence & Tisha Campbell-Martin, Martin

Martin Lawrence and Tisha Campbell-Martin played the roles of a blissfully married couple in the 1990s comedy series, Martin. However, their real-life relationship was quite different. In a surprising turn of events during the fourth season, Tisha abruptly left the show and filed a lawsuit against Martin Lawrence, alleging misconduct. According to reports, Campbell-Martin, who portrayed Lawrence's on-screen wife Gina from 1992 to 1997, accused him of exhibiting "repeated and escalating" inappropriate behavior along with associated threats. Fortunately, the case was ultimately resolved without proceeding to court.

Martin Lawrence & Tisha Campbell-Martin – Martin.jpg @Surviving Martin | WHAT REALLY HAPPENED BETWEEN MARTIN & TISHA CAMPBELL/True Celebrity Stories/YouTube.com

Debra Messing & Megan Mullaly, Will and Grace

Despite their return for a reboot in 2018, the stars of Will and Grace, Debra Messing and Megan Mullally, who portrayed Grace and Karen respectively, reportedly did not have a harmonious relationship on set, according to various reports. Rumors circulated about an ongoing feud, which resulted in Mullally's absence from several episodes in the final season in 2020. Additionally, the co-stars followed other castmates on social media but did not follow each other.

Debra Messing & Megan Mullaly – Will and Grace.jpg @Megan Mullally to Miss ‘Will & Grace’ Episodes Amid Feud Rumors/Us Weekly/YouTube.com

Lauren Conrad & Heidi Montag, The Hills

When The Hills premiered in 2006, it quickly became a cultural phenomenon. The captivating reality drama followed the journey of Lauren Conrad, a former cast member of Laguna Beach, as she navigated the streets of Los Angeles. Conrad's on-screen persona portrayed a young woman with exceedingly high expectations for her friends. It seemed that the only way to stay in Conrad's favor was to pledge unwavering loyalty to her. Any deviation from her expectations often resulted in tense arguments, particularly in the lively club scenes.

Lauren Conrad & Heidi Montag – The Hills.jpg @Why Heidi Montag Thinks Lauren Conrad Should Be As Rich As Kylie Jenner/Access Hollywood/YouTube.com

Will Smith & Janet Hubert, The Fresh Prince of Bel-Air

The tension between Will Smith and Janet Hubert came as a surprise to fans of The Fresh Prince of Bel-Air. Hubert, who portrayed Aunt Viv on the show from 1990 to 1993, was ultimately let go due to creative differences with Smith. In 2011, she referred to the actor as an "egomaniac." Hubert continued to speak out against Smith in 2013, stating that he and Alfonso Ribeiro had done "terrible, horrible things" to her, likening their behavior to that of misbehaving children. Daphne Maxwell Reid replaced Hubert as the matriarch for the final three seasons of the TV series.

Will Smith & Janet Hubert – The Fresh Prince of Bel-Air.jpg @Will Smith, Janet Hubert Discuss Feud During 'Fresh Prince' Reunion/ET Canada/YouTube.com

Jerome Flynn & Lena Headey, Game of Thrones

The tension between Lena Headey and Jerome Flynn, who both appeared in Game of Thrones, was not caused by any conflicts related to the show itself. Instead, it stemmed from their past romantic relationship. Headey and Flynn dated in the early 2000s, and according to sources close to the couple, their breakup was so acrimonious that they have been unable to communicate with each other ever since. A member of the Game of Thrones team revealed to The Telegraph that Headey and Flynn are no longer friends and go to great lengths to avoid being in the same room together. Despite efforts to reconcile their differences at one point, it seems they are now advised to be kept apart under any circumstances.

Jerome Flynn & Lena Headey – Game of Thrones.jpg @Game Of Thrones Season 7 FINALE: Why Bronn left the Dragonpit Scene early?/Core Of Attention/YouTube.com

Chad Michael Murray & Sophia Bush, One Tree Hill

The romance between Chad Michael Murray and Sophia Bush during their time on One Tree Hill was filled with ups and downs. The two actors got married in 2005, coinciding with the show's second season, but their marriage ended in divorce within a short period of less than six months. Despite their split, they continued to work alongside each other on the CW series until Murray's departure in 2009. In a 2018 interview, Bush was asked about their relationship, and she responded with humor, saying, "Everyone was 22 and dumb, you know?" She joked about the marriage, stating that it wasn't something she particularly wanted to do, but it was okay.

Chad Michael Murray & Sophia Bush – One Tree Hill.jpg @Chad Michael Murray's Wife Sarah Roemer Pokes Fun At Sophia Bush's Marriage Claims/Access Hollywood/YouTube.com

Ashley Tisdale & Lucas Grabeel, High School Musical

Tisdale and Grabeel first crossed paths during the 2006 Disney musical sensation, High School Musical, where they portrayed fame-hungry siblings Sharpay and Ryan Evans. While their on-screen chemistry may have been convincing, the actors were not friends during the filming of the HSM franchise. Tisdale candidly addressed their relationship when they reunited in 2017 on her YouTube channel. With a laugh, she revealed, "We were not close. We were not best friends—let's face it. It's been ten years, so we can talk about it." She added, “We disliked each other. I'm dead serious.”

Ashley Tisdale & Lucas Grabeel – High School Musical.jpg @What I've Been Looking For | High School Musical | Disney Channel/Disney Channel/YouTube.com

Leonard Nimoy & William Shatner, Star Trek

Leonard Nimoy and William Shatner will be forever remembered as iconic figures in the Star Trek franchise and one of the most remarkable duos in Hollywood. According to Shatner, their journey started off with a competitive dynamic on stage but eventually evolved into a close friendship and partnership that spanned several seasons, resembling that of unique siblings.

Leonard Nimoy & William Shatner – Star Trek.jpg @Star Trek's William Shatner opens up about Leonard Nimoy - BBC News/BBC News/YouTube.com

Amanda Bynes and Jennie Garth, What I Like About You

The sitcom What I Like About You follows the contrasting personalities of Holly (Amanda Bynes) and her more conservative older sister Val (Jennie Garth). While their characters may have had their differences, they ultimately shared a sisterly bond. Regrettably, the same cannot be said for the actresses themselves. Bynes and Garth allegedly had frequent conflicts on set, with Amanda even referring to Jennie as the "meanest actress who ever walked onto a television set." During a conversation with Jeff Probst, host of Survivor, Garth revealed that she contemplated giving up acting after the show concluded.

Amanda Bynes and Jennie Garth – What I Like About You.jpg @Tribute to Jennie Garth and Amanda Bynes/Danielle Schwerin a/YouTube.com

James Franco & Busy Phillips, Freaks & Geeks

The alleged conflict between James Franco and Busy Philipps reportedly started during their time working on the show Freaks & Geeks. According to Philipps, Franco physically threw her to the floor without her consent or knowledge during a scene. Distressed by the incident, Philipps confided in her co-star Linda Cardellini, who advised her to report it to their supervisor. As per Philipps, Franco eventually acknowledged the incident after being prompted by the show's director and creators. However, despite being asked to apologize, Philipps claims that Franco faced no consequences for his alleged actions.

James Franco & Busy Phillips – Freaks & Geeks.jpg @l Busy Philipps l James Franco l Freaks and Geeks l This Will Only Hurt a Little/#APEX CROWN/YouTube.com

Miley Cyrus & Emily Osment, Hannah Montana

Maintaining their on-screen friendship proved to be a challenge for the two actresses behind the beloved characters. Miley Cyrus opened up about her off-screen relationship with Emily Osment in her diary, Miles to Go. She shared her disappointment, stating, "The show felt real to me, and I wanted my relationship with Lilly to feel real too. I knew it didn't have to be—Broadway is the stage—but I was disappointed." However, the co-stars eventually worked through their differences and are now good friends. They recently had an Instagram reunion to celebrate the ten-year anniversary of Hannah Montana.

Miley Cyrus & Emily Osment – Hannah Montana.jpg @Miley Cyrus and Emily Osment BFF moments/lesbianforlovato/YouTube.com

Lauren Graham & Scott Patterson, Gilmore Girls

Fans adored the transition from friendship to romance between Luke and Lorelai on Gilmore Girls, but off-screen, the dynamic between Lauren Graham and Scott Patterson was less than ideal. In an interview, Lauren admitted that she and Scott were not friends. However, she maintains that any reports of a feud are greatly exaggerated. According to Lauren, she and Scott have a perfectly fine working relationship. In a conversation with TV Guide in 2007, the Gilmore Girls star addressed the rumors and aimed to dispel any misconceptions about their relationship.

Lauren Graham & Scott Patterson – Gilmore Girls.jpg @Scott Patterson Is 'Excited' To Watch 'Gilmore Girls' Episodes For 'I Am All In' Podcast | EXTENDED/ET Canada/YouTube.com

Bill Murray and Lucy Liu, Charlie’s Angels

Charlie's Angels (2000), a film adaptation of the television series, is an action-comedy that revolves around a close-knit group of characters. However, off-screen, not all the relationships were harmonious. Lucy Liu, known for her role as Alex Mundy, revealed that a conflict arose between her and Bill Murray, who portrayed John Bosley, due to a scene being altered without Murray's awareness. Liu further explained that during the filming of the scene, Murray insulted her by suggesting that she didn't "deserve" to be there alongside Cameron Diaz and Drew Barrymore.

Bill Murray and Lucy Liu – Charlie’s Angels.jpg @Drew Explains Lucy Liu's Clash with Bill Murray on Charlies Angels Set | Drew's News/The Drew Barrymore Show/YouTube.com

Alyssa Milano & Rose McGowan, Charmed

Alyssa Milano seems to have had strained relationships with multiple co-stars throughout her career. After her turbulent rapport with Shannen Doherty, it appears that her connection with Rose McGowan, who replaced Doherty on the show, was also far from amicable. Despite their characters being close on-screen, their real-life relationship seems to have been filled with bitterness. In a tweet from 2020, McGowan expressed that she cried every time the show got renewed because Milano allegedly made the set a toxic environment. The tweet suggests ongoing animosity between the two actresses.

Alyssa Milano & Rose McGowan – Charmed.jpg @‘charmed’ feud: rose mcgowan slams alyssa milano as ‘fake’ — ‘you make me want to vomit’/Celebrity News/Celebrity Star/YouTube.com

Matthew Fox & Dominic Monaghan, Lost

Despite their on-screen chemistry, the relationship between the actors Matthew Fox and Dominic Monaghan, who played Jack and Charlie in the series Lost, was far from amicable in real life. This came as a surprise to many viewers. In May 2012, during a Twitter Q&A session, Monaghan was asked to encourage Fox to join the social media platform. In his response, Monaghan didn't hold back and publicly stated, "He is a woman beater. Thank you, but no thanks." This statement shed light on the strained relationship between the two actors.

Matthew Fox & Dominic Monaghan – Lost.jpg @Dominic Monaghan Claims Matthew Fox Beats Women/FirstRace TV/YouTube.com

Ariana Grande & Jennette McCurdy, Sam & Cat

Grande and McCurdy rose to prominence through their roles in Victorious and iCarly, respectively. Following the conclusion of these shows, Nickelodeon decided to create a spin-off called Sam and Cat, featuring both actresses as the main characters. However, their collaboration came to an abrupt halt when explicit photos of McCurdy were leaked online in March 2014. McCurdy chose to skip the Kid's Choice Awards, leading many to speculate that it was a consequence of the leak. However, TMZ reported that McCurdy's absence from the event was actually due to her discovery that Grande was being paid a significantly higher amount than her for their work on Sam and Cat.

Ariana Grande & Jennette McCurdy – Sam & Cat.jpg @Jennette McCurdy Hopes Ariana Grande Reads Her Memoir (Exclusive)/Entertainment Tonight/YouTube.com

Lucille Ball & Vivian Vance, The Lucy Show

During its run from 1962 to 1968, The Lucy Show featured a dynamic cast, with Lucille Ball and Vivian Vance as co-stars for the first three seasons. However, there was some tension between Ball and Vance throughout their collaboration. The strain can be traced back to the time when Vance was cast as Ethel Mertz on I Love Lucy, a role given to her by Desi Arnaz. As the seasons progressed, rumors circulated that Vance was seeking a higher salary, while Ball was not willing to negotiate.

Lucille Ball & Vivian Vance – The Lucy Show.jpg @The Lucy Show - "Christmas Caroling" - 1962 - Lucy & Vivian - Lucille Ball - Vivian Vance/A FUSCO/YouTube.com

Rachel McAdams & Ryan Gosling, The Notebook

Despite their undeniable on-screen chemistry and subsequent real-life relationship, Ryan Gosling and Rachel McAdams did not get along while filming The Notebook. The tension between them was so intense that at one point, Gosling even tried to have McAdams removed from the set. Director Nick Cassavetes revealed this in an interview with VH1, stating, ‘’They were really not getting along one day on set. Really not. And Ryan came to me, and with 150 people standing in this big scene, he says, ‘Nick, come here.’

Rachel McAdams & Ryan Gosling – The Notebook.jpg @What Happened Between Ryan Gosling & Rachel McAdams | Rumour Juice/Rumour Juice/YouTube.com

Alyssa Milano & Shannen Doherty, Charmed

Milano and Doherty played sisters and best friends on the show. Fans were devastated when Doherty's character Prue was killed off in the third season of Charmed, as the bond between the three Halliwell sisters was a central part of the series. Milano openly admitted the animosity between them, stating, "We didn't get along." The production team even brought in a counselor in an attempt to resolve the conflict, but Milano and her co-star Holly Marie Combs claim that this intervention only made things more difficult.

Alyssa Milano & Shannen Doherty – Charmed.gif @Alyssa Milano On Shannen Doherty After Past Tension On "Charmed"!/1 CELEBRITY NEWS/YouTube.com

Kirk Cameron & Julie McCullough, Growing Pains

Once Kirk Cameron discovered about Julie McCullough's previous involvement with Playboy, he expressed his disapproval of her presence on the '80s sitcom Growing Pains. After Cameron's character, Mike Seaver, proposed to McCullough's character Julie Costello, he confronted the show's producer and insisted that the wedding should not take place. According to McCullough, Cameron was upset about her nude photographs, which resulted in her appearing in only a few episodes of the ABC show. However, Cameron maintains that her character was never intended to be a long-term part of the series.

Kirk Cameron & Julie McCullough – Growing Pains.jpg @The TRUTH About Julie McCullough and TV's "Growing Pains"/Dave Sundstrom/YouTube.com

Jason Segel & Alyson Hannigan, How I Met Your Mother

Despite their characters' strong romantic connection on How I Met Your Mother, Alyson Hannigan and Jason Segel had a strict no-kissing policy on set. This was primarily due to Hannigan's aversion to tobacco smoke, as Segel was a smoker. In a 2008 interview, Hannigan candidly expressed her dislike for the smell and taste of tobacco smoke, likening it to "kissing an ashtray." Although Segel made efforts to freshen his breath with gum or mints, it didn't alleviate the issue for Hannigan. As a result, they decided to avoid on-screen kissing scenes to accommodate Hannigan's sensitivity to tobacco smoke.

Jason Segel & Alyson Hannigan – How I Met Your Mother.jpg @Cast Of 'How I Met Your Mother' Play 'Finish The Line' | Cover Shoot | Entertainment Weekly/Entertainment Weekly/YouTube.com

Blake Lively & Leighton Meester, Gossip Girl

Throughout the six episodes of Gossip Girl, Serena and Blair encountered numerous conflicts, including overlapping romantic interests, intricate schemes, and even a memorable cake fight. However, they always managed to reconcile and support each other in the end. In contrast, the real-life relationship between the actresses behind the characters, Blake Lively and Leighton Meester, was not as harmonious. Speculations arose about their alleged discord, and Lively's publicist chose not to address the issue directly. In August 2010, comments from Lively's publicist were released, stating that Blake and Leighton were never close friends and simply maintained a professional relationship, with Lively focusing on her work and personal life outside of the set.

Blake Lively & Leighton Meester – Gossip Girl.jpg @Gossip Girl Cast: Relationship They Have In Real Life | ⭐OSSA/OSSA/YouTube.com

Jay Mohr & Jennifer Aniston, Picture Perfect

Aniston's reaction to actor Jay Mohr replacing her then-boyfriend Tate Donovan as her on-screen love interest in Picture Perfect was far from enthusiastic. Instead of directing her resentment towards the studio, Aniston directed it towards Mohr himself. In a 2010 interview, Mohr described it as one of the most unpleasant filming experiences he had ever encountered. He shared how being on set with a leading lady who was dissatisfied with his presence and made it clear from the very beginning made it a challenging and difficult situation.

Jay Mohr & Jennifer Aniston – Picture Perfect.jpg @Jennifer Aniston & Jay Mohr [Picture Perfect] || It Will Rain/Lucia Agudo/YouTube.com

Isaiah Washington & Patrick Dempsey, Grey’s Anatomy

In 2006, Isaiah Washington, known for his role as Burke on Grey's Anatomy, was let go from the show following his use of a derogatory word aimed at his co-star T.R. Knight, who played O'Malley. The incident escalated into a physical altercation with Patrick Dempsey, who portrayed Shepherd, on the set. Subsequently, Knight made the decision to publicly disclose his sexual orientation. The controversy resurfaced when Washington repeated the offensive remark offstage at the Golden Globes in 2007, reigniting the heated discussion. In June of the same year, ABC officially announced that they would not be renewing Washington's contract.

Isaiah Washington & Patrick Dempsey – Grey’s Anatomy.jpg @Grey's' Writers Detail Patrick Dempsey and Isaiah Washington's Fight/Kamran TV/YouTube.com

Shirley MacLaine and Debra Winger, Terms of Endearment

The 1983 film Terms of Endearment portrays the story of Aurora (Shirley MacLaine), a meticulous woman on a quest for true love, while her daughter, Emma (Debra Winger), grapples with marital problems. Although their characters shared a beautiful mother-daughter relationship on-screen, the real-life dynamic between the actresses was reportedly quite the opposite, marked by intense conflict and even physical altercations. In a 1986 interview with The New York Times, Debra Winger did not deny the rumors and openly acknowledged, “I can't deny that we fought.”

Shirley MacLaine and Debra Winger – Terms of Endearment.jpg @How Debra Winger Farted in Shirley MacLaine’s Face Causing a FEUD?/Age Of Vintage 2/YouTube.com

Gene Kelly & Debbie Reynolds, Singin’ in the Rain

Singin' in the Rain, the beloved musical, captured the hearts of many, but the behind-the-scenes experience wasn't enjoyable for some of its actors. In her memoir, Unsinkable, Reynolds reflected on her time on set with Kelly, recalling, "He attended rehearsals and criticized everything I did, never offering a word of encouragement." She also shared her experience of their characters' on-screen kiss. In her memoir, she wrote, “Kelly took me firmly in his arms...and forcefully kissed me. 'Eeew! What was that?' I exclaimed, breaking free from his embrace and spitting.”

Gene Kelly & Debbie Reynolds – Singin’ in the Rain.jpg @Chantons Sous La Pluie - Bande Annonce Officielle (VOST) - Gene Kelly / Debbie Reynolds/Warner Bros. France/YouTube.com

Billy Gardell & Melissa McCarthy, Mike and Molly

According to a tabloid publication, there are reports of tension between Billy Gardell and Melissa McCarthy, who portrayed an on-screen couple on the show Mike & Molly. The publication suggests that Billy perceives himself as the true star of the show, while Melissa receives more attention and enjoys it. This alleged dynamic is said to be causing animosity between them, and the tension is said to be escalating. It's important to note that these reports are from a tabloid publication and should be taken with a grain of salt, as the true nature of their relationship may differ from what has been speculated.

Billy Gardell & Melissa McCarthy – Mike and Molly.jpg @This Is Actually Why Mike & Molly Got Canceled/Facts Verse/YouTube.com

Joan Collins & John Forsythe, Dynasty

During an appearance on a talk show, Joan Collins revealed that she and her co-star had a complete season without speaking to each other. Recounting the incident at the People's Choice Awards, she explained, “We won all the categories, and we were told that when we were receiving the award, it would be given to John. However, they presented it to me. He didn't handle it well. I said, 'Oh, thank you very much, I will give it to our fearless director,' and he responded with, 'She's said enough,' and that was it. It was a very unpleasant experience, I have to say.”

Joan Collins & John Forsythe – Dynasty.jpg @Dame Joan Collins hits out at late Dynasty co-star John Forsythe and their gender pay gap 707109/Debbie Reynolds/Celebrity Star/YouTube.com

Shannen Doherty & Jennie Garth, Beverly Hills, 90210

One of the most notorious feuds of the 1990s took place on the set of the hit series Beverly Hills, 90210. Shannen Doherty, known for her tough and confrontational attitude, frequently clashed with co-stars Jennie Garth and Tori Spelling. In 2015, Spelling revealed that she had influenced her father, Aaron Spelling, who was the show's producer, to fire Doherty. According to Spelling, Doherty and Garth were even involved in a physical altercation.

Shannen Doherty & Jennie Garth – Beverly Hills, 90210.jpg @The story behind the feud between Shannen Doherty and Jennie Garth/Stephen Sundstrom/YouTube.com

Sarah Jessica Parker & Kim Cattrall, Sex and the City

More than twenty years have passed since the premiere of the first season of Sex and the City, a show celebrated for its lavish fashion and romantic storylines. However, behind the scenes, there has been an ongoing and highly debated feud between Sarah Jessica Parker (Carrie) and Kim Cattrall (Samantha) that is often more intense than the on-screen drama. According to insider sources, Parker and Cattrall have been engaged in a long-standing disagreement regarding financial matters. When Parker was promoted to showrunner during the second season, her salary reached $300,000, which reportedly prompted Cattrall to request a raise.

Sarah Jessica Parker & Kim Cattrall – Sex and the City.jpg @Samantha RETURNS! Kim Cattrall Joins And Just Like That | E! News/E! News/YouTube.com

Stacy London & Clinton Kelly, What Not To Wear

Stacy London and Clinton Kelly have been close friends for many years, rising to fame together on What Not To Wear and supporting each other throughout their careers. However, in 2018, a disagreement occurred between them, leading Stacy to unfollow Clinton on Twitter. This action was seen by Clinton as a significant snub, describing it as a "smack in the face" in a later statement.

Stacy London & Clinton Kelly – What Not To Wear.jpg @Farewell from Stacy and Clinton | What Not to Wear/TLC/YouTube.com

Marlyn Monroe & Tony Curtis, Some Like It Hot

Tony Curtis took a less than pleasant route when asked about his experience kissing his co-star, Marilyn Monroe, in the film Some Like It Hot. Rather than offering a positive response, he described it as "like kissing [a tyrant]." Prior to filming, Curtis and Monroe had been in a romantic relationship, but their feelings had changed once they started shooting. Curtis noted that Monroe's behavior had become erratic, saying, "She'd gone funny. Her mind was all over the place." He then went on to discuss a specific scene on a yacht where they had to kiss, describing it as "horrendous." According to Curtis, Monroe nearly choked him by forcefully inserting her tongue down his throat into his windpipe.

Marlyn Monroe & Tony Curtis – Some Like It Hot.jpg @What REALLY Happened Between Marilyn Monroe & Tony Curtis/Facts Verse/YouTube.com

Patrick Swayze & Jennifer Grey, Dirty Dancing

Dirty Dancing is undoubtedly a beloved classic, known for its memorable soundtrack and mesmerizing dance sequences. The on-screen chemistry between Jennifer Grey's character, Baby, and Patrick Swayze's character, Johnny, is undeniable. However, behind the scenes, their relationship was far from harmonious. It is said that they would frequently engage in arguments before filming each scene. Despite the tension, Jennifer Grey has acknowledged that their clashes actually contributed to their scintillating on-screen chemistry. Since the film's release, Grey has only expressed positive sentiments about her late co-star, Patrick Swayze.

Patrick Swayze & Jennifer Grey – Dirty Dancing.jpg @Patrick Swayze and Jennifer Grey Couldn’t Stand Each Other/Facts Verse/YouTube.com

Dustin Hoffman & Meryl Streep, Kramer vs. Kramer

The tension between Dustin Hoffman and Meryl Streep on the set of the 1979 Oscar-winning film was more akin to a clash between actors rather than the characters they portrayed in Kramer vs. Kramer. The book Her Again: Becoming Meryl Streep, released in April 2016, shed light on the intense conflict that unfolded during the film's production. Hoffman, known for his method acting approach in portraying Ted Kramer, went as far as slapping then-up-and-coming actress Streep (playing Joanna Kramer) across the face during a heated scene. He also made provocative comments about her late boyfriend, John Cazale, who had passed away from lung cancer.

Dustin Hoffman & Meryl Streep – Kramer vs. Kramer.jpg @Meryl Streep Recalls Dustin Hoffman's 'Kramer vs. Kramer' Slap: "It Was Overstepping" | THR News/THR News/YouTube.com

Kenny Baker and Anthony Daniels, Star Wars

The strained relationship between the characters C-3PO and R2-D2 in the Star Wars films was well-known, yet it was clear that the two droids had a certain level of care for each other. However, the same cannot be said for the actors who portrayed them, Kenny Baker and Anthony Daniels. Despite being the only two actors to appear in all of the franchise's movies (until Baker's death in 2016), they never formed a strong connection. Over the years, they frequently exchanged jabs and criticisms. Nevertheless, when Baker passed away, Daniels expressed his condolences on Twitter, showing a moment of respect despite their differences.

Kenny Baker and Anthony Daniels – Star Wars.jpg @The Real Life 3PO/R2 Star Wars Feud/ThatJunkman/YouTube.com

Terrence Howard & Robert Downey Jr. – Iron Man

The initial release of Iron Man marked a significant success for the Marvel Cinematic Universe. However, despite the apparent harmony during the production of the first film, the atmosphere had soured by the time the sequel was in development. Terrence Howard, who portrayed Colonel James Rhodey Rhodes in the first installment, was replaced by Don Cheadle for Iron Man 2 due to salary disputes. Howard attributed this decision to his co-star Robert Downey Jr., but Downey has denied any involvement, stating, “I had nothing to do with that decision.”

Terrence Howard & Robert Downey Jr. – Iron Man.jpg @La “traición” de Robert Downey Jr. a Terrence Howard/Upsocl/YouTube.com

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